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10.1002/jnr.21372 [DOI] [PubMed] [Google Scholar] Ko K

Follow these rules from day one

Increased availability of serotonin precursors augments the amount of available serotonin, which might lead to the development of the serotonin syndrome [182] and, thereby, the involvement of both 5-HT1A and 5-HT2A receptors

This reduces pain and lowers the chance of problems
