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Both environmental hypoxia and body hypoxia cause neuronal damage in the brain [22]
References "Assessment of the Efficacy of Cryolipolysis on Abdominal Fat Deposits: A Prospective Study," Aesthetic Plastic Surgery , May 3, 2023

36,37 Zonula occludens (ZO), including ZO-1 and its homologs ZO-2 and ZO-3, is a group of PDZ-related scaffolding proteins that belong to the superfamily of membrane-associated guanylate kinase-like proteins, possessing sites of three tandem PDZ domains at the N-terminus 38,39 (Figure 1)

Theranostics (2020) 10(13):580214
