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Description
These results indicate that LPD-3 antagonizes effects of SAMS-1 in PC accumulation in ER membranes, again supporting a physiological role of LPD-3 in facilitating the ER-to-PM trafficking of phospholipids, which reduces PC accumulation in ER membranes
An initial limitation may be the lack of methodology given that they did not present muscle biopsies, highlighting whether it was possible to increase the content of muscle carnitine
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examined the expression of CPT-1 isoforms in photoreceptor cells and retinal pigment epithelial cells that are known to be affected morphologically and functionally in complete MTP deficiency and deficiency of long-chain 3-hydroxyacyl-CoA hydratase (LCHAD) [167]
