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When extreme cold contacts the skin, blood vessels constrict dramatically in a process called vasoconstriction

doi: 10.2147/DDDT.S426870 75

Collectively, these data suggest that OspC-mediated ADP-riboxanation of SEPT9 at Arg561 impairs salt bridges and disrupts the SEPT9-SEPT9 NC-interface, thereby preventing septin recruitment and S
