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Description
We examine the chemistry employed in designing liraglutide and semaglutide, the human and non-human studies used to investigate their cellular targets and pharmacological effects, and ongoing investigations into new applications and formulations of these drugs

Frontiers in Pharmacology, 12 , 627533

Given that cortisol can suppress the ability of the hypothalamus to secrete CRH, it makes sense that exogenous corticosteroids from outside the body may also suppress the entire HPA axis

Using a vial beyond 28 days means injecting a solution with unknown potency and potentially elevated bacterial contamination
