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Thus, Nrf2/ARE activity is essential for combating oxidative stress and facilitating cellular repair (Re et al., 2014)

Sperm Oxidative Stress during In Vitro Manipulation and Its Effects on Sperm Function and Embryo Development
Additionally, elevated mRNA levels of histamine N -methyltransferase (HMT), the enzyme responsible for histamine inactivation via methylation, were detected in both the substantia nigra and putamen