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The competition between NA methylation and NAD + salvage indicates that NNMT might limit fuel oxidation and promote fat storage, because if the activity or expression of NNMT is high, then, NA might not be salvageable, thus limiting the NAD + -dependent processes [16]

5-amino-1MQ also led to a 30%+ reduction in adipocyte size, a 40%+ decrease in adipocyte volume, and a 30% reduction in total cholesterol levels [3]

The most common side effects nausea, constipation, and fatigue can all be alleviated by adding vitamin B12

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