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There was even a theory originally put out in the 1950s called The Free Radical Theory of Aging* which basically held that we age by rusting from within, due largely (but not exclusively) to free radical damage

Infect Immun 70:43364343 Leite F, Atapattu D, Kuckleburg C, Schultz R, Czuprynski CJ (2005) Incubation of bovine PMNs with conditioned medium from BHV-1 infected peripheral blood mononuclear cells increases their susceptibility to Mannheimia haemolytica leukotoxin

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The Phase 2 clinical trial showed roughly 2-3 kg more fat loss than placebo over 12 weeks, with no impact on blood sugar, insulin, IGF-1, or any hormonal marker
