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Alkylation was performed with 20 mM iodoacetamide at RT for 45 min in the dark

A review published by the World Health Organization estimated that in 2012 alone, there were about 273 million cases of curable STIs among adults aged 1549, including 128 million cases of chlamydia, 27 million cases of gonorrhea, 101 million cases of trichomoniasis, and 18 million cases of syphilis

The trans effect determines the polarizability of the CoC bond so formed

It is important to emphasize that although certain research progress has been made, our work is still at the preclinical stage and remains some way from clinical application