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doi: 10.1074/jbc.M310529200

Angular cheilitis Affects about 0.7% of the general American population, with a higher incidence among the elderly (11%) and denture wearers (28%) Cause cracks, sores, and inflammation at the corners of the mouth Common cause: Excessive saliva exposure leading to skin damage and infection Other causes: Atopic dermatitis, long-term use of certain medications, nutritional deficiencies, and chronic illnesses like diabetes and inflammatory bowel disease Conditions severity: Mild redness to severe, potentially bleeding cracks and crusting More prevalent in children, the elderly, and denture wearers

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