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NORSE and FIRES are defined below: Epilepsia partials continua (EPC) is defined & discussed here: NORSE NORSE definitions New-onset Refractory Status Epilepticus (NORSE) : New-onset seizure with refractory status epilepticus (i.e., refractory to two medications such as benzodiazepine plus levetiracetam)

One potential motive for the inefficiency of CoQ 10 supplementation against fatigue in healthy subjects might be due to the baseline and change percentage of CoQ 10 plasma levels

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This addresses the poor aqueous stability of LF and its high excretion through the nasolacrimal duct, which can affect its therapeutic efficacy
