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Emotional trauma : Past traumas, PTSD, and emotional stress, including those in the earliest year of life, can have a lasting impact on HPA axis regulation even years after the traumas occur

Konopleva M, Zhao S, Jiang S, Snell V, Zhang X, Reed JC, Andreeff M

Histone modification Histones modification, such as methylation, demethylation, acetylation and deacetylation, remodels the chromatin architecture which dictates histones either loosening or tightening their grip onto DNA to regulate MSC self-renewal, senescence and differentiation potential