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Description
Mechanistically, impaired iron exporte.g., zinc-mediated inhibition of amyloid precursor protein (APP) ferroxidase activityprovides a route to local iron accumulation (Duce et al., 2010), while familial AD presenilin mutations confer selective vulnerability to ferroptosis in human neuronal models (Greenough et al., 2022)
The efficacy plummets
To estimate cortical or whole-brain RSFC within a specific functional network or a ROI, we averaged the RSFC across all vertices within the network or region
B.AguilarM.et al
