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NAC dose was titrated from 1200 mg per day to 3000 mg per day, and duration of the trial was 12 weeks

For negative-mode acquisition, mobile phase A was 100% LCMS-grade H 2 O with 10 mM ammonium acetate, 0.1% ammonium hydroxide and 0.1% medronic acid (Agilent)

Nat Rev Microbiol 2019, 17 (3), 167180

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