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Reactive oxygen species (ROS), traditionally viewed as damaging metabolic byproducts, are now recognized as critical signaling molecules in the brain, where they modulate various neural functions including synaptic plasticity, neurogenesis, and circadian rhythm regulation

Recent studies in our laboratory have shown that Cistanches Herba and Cynomorii Herba (two Yang-invigorating herbs) can fluidize the mitochondrial inner membrane, causing a small increase in ROS production

A., Nejatisafa A

Using a combined COMT-I/LDopa treatment in PD patients has also shown to be effective in lowering Hcy levels and PN incidence when compared to oral LDopa alone (Andrasson et al