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These radicals are highly reactive and can abstract hydrogen atoms from the carbon atoms at the bis-allylic positions in PUFAs (59)

Consequently, adrenal hormone-related diseases like adrenal insufficiency and Cushings syndrome often show signs of oxidative stress, like fatigue, immune dysfunction, cognitive impairment, and accelerated aging (9)

In sterile conditions such as ischemic injuries, trauma, tumors, tissue transplants, and autoimmune diseases, robust immune responses could be elicited by DAMPs (50, 51)

Animal studies have shown a significant reduction in postoperative complications, particularly anastomotic dehiscence