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Although direct aldehyde modification of HuR by 4-HNE has not been definitively confirmed, multiple studies have shown that 4-HNEinduced oxidative stress activates signaling pathways that regulate HuR phosphorylation and dephosphorylation, significantly increasing its binding affinity for inflammatory mRNAs

Many of Nature Made s B12 and B-Complex supplements, like our Super B-Complex with C Tablets and Vitamin B12 Fast Dissolve Tablets, are USP Verified

10.1016/J.FOCHX.2024.101521

[DOI] [Google Scholar] Li H., Zhang Y., Ding J., Wu T., Cai S., Zhang W., Cai R., Chen C., Yang R
