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Description
In this method, intermittent bolus injections are locally administered into the brain, where the drugs further diffuse within the brain with minimal side effects [106]

Thompson et al., Regional Brain Trace-Element Studies in Alzheimers Disease

doi: 10.1182/bloodadvances.2021005246 278 BoeckelHKarstenCMGpelWHertingERuppJHrtelCet al

E., LipidMediated DNA and siRNA Transfection Efficiency Depends on Peptide Headgroup, Soft Matter 9, no
