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Description
4.5 Intranasal administration Drugs delivered to the olfactory region via IN can reach the olfactory bulb and other CNS regions within minutes via intracellular and extracellular pathways along the olfactory nerves or diffusion (especially for lipophilic small molecules), allowing for a higher concentration of the therapeutic agents in the brain compared to the bloodstream
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Magrioti V

New York [u.a.]: Oxford University Press

Br J Pharmacol 133: 8996, 2001
