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Research has shown that advanced glycation end-products (AGEs) accumulate in both human and animal diabetic nerves across all components of peripheral nerve tissues (60, 61)

NRF2 activators also regulate GSH levels through de novo synthesis and recycling [52,53]

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Ten trials 13,14,2632 had sufficient data for the meta-analysis (n=366 treatment, n=359 control), and five trials 15,26,3335 were excluded from quantitative synthesis due to incomplete or non-extractable data
