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Targeting the NLRP3 inflammasome in inflammatory diseases

At the end of the treatment, more patients in the pioglitazone groups achieved the primary outcome and resolution of MASH than did those in the placebo group, and pioglitazone significantly reduced the fibrosis scores

Inflammation is a key secondary pathological process in spinal cord injury, and KD attenuates inflammation, including reduced nuclear factor-kappa B pathway and expression levels of TNF-, IL-1, and interferon- (149)
