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Discussion Exploring the crosstalk mechanisms of apoptosis, ferroptosis, and pyroptosis ROS is an important factor in the processes of apoptosis, ferroptosis, and pyroptosis From the overview of apoptosis, ferroptosis, and pyroptosis in the text, we find that ROS play a significant role in the occurrence of these three types of cell death

When these reactions are mild, they typically aren't cause for concern

Pharmacological strategies include medications for T2DM (GLP-1 receptor agonists, SGLT2 inhibitors, biguanides, thiazolidinediones), lipid-lowering drugs (statins, cholesterol absorption inhibitors), antihypertensive drugs, hepatoprotective agents (UDCA, FXR agonists), probiotics/prebiotics/synbiotics targeting the gut microbiota, PPAR agonists, thyroid hormone receptor agonists (THR- agonists), fibroblast growth factor analogs (FGF19/FGF21), and newly developed DNL inhibitors (ACC inhibitors, FAS inhibitors, SCD1 inhibitors, DGAT inhibitors, ketohexokinase inhibitors, MPC inhibitors), miRNAs, and nanoparticles as drug delivery systems