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Description
Cellular assays Mammalian cell activity culture and characterization Passages 312 human dermal fibroblast (HDF, Lonza, Basel, Switzerland) were cultured in Dulbecco's Modified Eagle Medium (DMEM, Sigma Aldrich) supplemented with 10% fetal bovine serum (Hyclone, Logan, UT) and 1% penicillin/streptomycin (P/S, Sigma Aldrich) in a 37C, humidified, 5% CO 2 /95% air environment

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The discontinuation rate due to adverse events was 6% for CagriSema versus 3.7% for placebo

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