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Tissue-level deficiency of cobalamin is associated with an increase in the urinary and serum concentrations of an organic acid called methylmalonic acid, which is an alternative product of a cobalamin dependent pathway within the mitochondria

Allergic reactions , whilst rare, can occur and range from mild skin reactions to severe anaphylaxis

If you or a family member has a history of Lebers Optic Neuropathy, do not take B12, as it may cause permanent vision loss

Subcutaneous Options: Abdomen and Thigh While most B12 shots are injected into a muscle (intramuscular), they can also be given as a subcutaneous injection