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Upon binding with Cu 2+ , DDC forms a highly lipophilic complex, Cu(DDC) 2 , also known as CuET, which is considered the primary active form responsible for disulfirams antitumor effects ( 2 complex, which interferes with critical intracellular metabolic pathways and signal transduction, ultimately leading to cell death

For the nuclear magnetic resonance (NMR) measurements (Bruker AVANCE NEO 600), we dissolved the fully dried OKGM powder in D 2 O until complete dissolution and then transferred it to an NMR tube using a disposable pipette

Mice were group-housed on a normal lightdark cycle (07:0019:00 h) with free access to chow and water

Whole-body electromyostimulation to fight osteopenia in elderly females: The randomized controlled Training and Electrostimulation Trial (TEST-III)