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The basic science of articular cartilage: structure, composition, and function

Spindel ON, Yan C, Berk BC

These mediators, in turn, recruit more immune cells, establishing a vicious cycle that continually amplifies inflammatory cascades

Disruption of epidermal barrier integrity due to disturbance of the composition and function of the resident microbial community in the skin is significantly related to psoriasis, including some skin fungal flora ( Candida albicans ) and bacterial flora ( Corynebacterium species), which might induce the accumulation of Th17 cells (Zielinski et al., 2012
