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10.1007/s00709-014-0670-8 28 ChenJ.-C.HoF.-M.Pei-Dawn Lee ChaoC.ChenC.-P.JengK.-C
The clinical signal began with a phase 1b study showing that concomitant cagrilintide plus semaglutide 2.4 mg was well tolerated in healthy volunteers, [6] and a phase 2 trial in people with type 2 diabetes and overweight, where CagriSema produced numerically greater weight loss (~15.6%) than semaglutide (~5.1%) or cagrilintide (~8.1%) alone