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N Engl J Med 371(20):18771888

Rats with trinitrobenzene sulfonic acid-induced colitis that received dietary glutamine supplementation (20 g/kg or 40 g/kg

doi: 10.1161/01.STR.0000252027.53766.2b
T-cell death as a barrier to sustained antitumor immunity Beyond functional exhaustion and the complex signaling networks that regulate T-cell activity, the physical elimination of tumor-reactive T cells within the TME represents a criticalyet often overlookedmechanism that limits the durability of antitumor immunity
