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Description
Discovery of GluN2A-selective NMDA receptor positive allosteric modulators (PAMs): tuning deactivation kinetics via structure-based design

There was Nos1 (decreased expression), Nos2 (increased expression), Plcg1 (decreased expression), Prkcg (increased, and then decreased expression), Ptgs2 (increased expression), and no effect on Nos3 and Ptk2

Its been studied more extensively than most growth hormone secretagogues because it received FDA approval for visceral fat reduction in HIV-associated lipodystrophy, which means it has a well-documented safety and efficacy profile in humans

Full scan mass spectra (350-1,400 m/z, 60,000 resolution) were detected in the Orbitrap analyzer with an automatic gain control (AGC) target of 4e 5 , automatic maximum injection time (auto max IT)
