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Regenerative medicine: current therapies and future directions

Under oxidative stress these three systems work in concert to detoxify ROS and lipid peroxides, maintain protein structure and function via thiol repair, prevent activation of redox-sensitive inflammatory pathways, and preserve mitochondrial membrane integrity and prevent apoptosis

GRB2, a HER2 adaptor protein, binds BECN1 to inhibit autophagy by suppressing VPS34 activity 38

Queval and Noctor, 2007)
