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[DOI] [PubMed] [Google Scholar] 2.European Commission Health and Food Safety Opinion on Caffeine, Taurine and D-Glucurono--Lactone as Constituents of So-Called Energy Drinks

Perimenopause, the transitional phase typically beginning in a woman's early-to-mid 40s and lasting four to eight years before the final menstrual period, is defined by erratic and declining ovarian hormone production

Initial presentation scenarios warranting GP consultation include: Abnormal liver function tests (elevated ALT, AST, or GGT) detected during blood work or health screening Incidental finding of hepatic steatosis on ultrasound, CT, or MRI performed for other indications Persistent unexplained fatigue, particularly when accompanied by metabolic risk factors Right upper quadrant discomfort or sensation of abdominal fullness Presence of multiple metabolic syndrome components (central obesity, hypertension, dyslipidaemia, impaired glucose regulation) Urgent medical attention is required if symptoms suggest advanced liver disease or acute complications