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N 2 adsorption isothermal analysis displayed an apparently lower surface area of Hb@ZIF-8 (663.8 m 2 /g) than 850.3 m 2 /g of ZIF-8 alone, elucidating the partial occupation of ZIF-8 pores by Hb (Supplementary Fig
doi: 10.1371/journal.pone.0248777
When B12 is deficient, demyelination occurs, particularly affecting the spinal cord's posterior columns (responsible for proprioception and vibration sense) and lateral corticospinal tracts (controlling motor function)
