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Description
lncRNA LINC01255 regulated the senescence of hMSCs by inhibiting the transcription of MCP-1 [151]
These are zinc-ion containing endopeptidases that are Ca +2 -dependent and currently constitute a family of 21 MMP's
Lonafarnib also inhibited cell proliferation and growth in a glioma cell line overexpressing EGFR, and induced arrest in the G 2 phase of the cell cycle by reducing pMAPK levels [374]
This is leading to investment in clinical trial spending which will further market penetration
