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Melanin Index Reduction In randomized, double-blind, placebo-controlled clinical trials, dermatologists monitored the skin changes of participants using a specialized spectrophotometer to track their Melanin Index (MI)

Tukey, Nrf2-Keap1 signaling pathway regulates human UGT1A1 expression in vitro and in transgenic UGT1 mice
Fedrizzi B, Pardon KH, Sefton MA, Elsey GM, Jeffery DW

Neutrophils release S100A8/A9 into the extracellular environment via NETosis, and this release further exacerbates neutrophil-mediated inflammation [262, 285, 310]
