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IBS is a function problem
Phytochemicals, bioactive constituents of medicinal plants, offer a compelling adjunctive approach for targeting the inflammatory, fibrotic, and neuroendocrine abnormalities seen in CIRS
23 Unlike initial T-cell activation, the activation of memory T cells no longer depends on antigen-presenting cells and can induce a stronger immune response
Of note, ABHD5 can bind multiple PNPLA family members (37, 70-72), suggesting that it functions as scaffold for forming various enzymatic assemblies, or metabolons, to mediate a wide array of metabolic processes
