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While traditional biomarkers may be insufficient in the early stages of this process, new-generation biomarkers and multi-omic approaches hold the potential to contribute to the improvement of disease diagnosis and prognosis

10.1159/000444063 148 LevyD.ZochodneD

Prevention of aflatoxin B 1 hepatoxicity by dietary selenium is associated with inhibition of cytochrome P450 isozymes and up-regulation of 6 selenoprotein genes in chick liver

In the nucleus, tAIF binds histones, inducing large-scale DNA fragmentation and chromatin condensationa caspase-independent process distinct from apoptotic DNA laddering [70]
