glutathione cleavable linker Chemical structures of linkers used in ADCs development. (a) Key Glycosidase-Cleavable Linkers in ADC design
Description
10.1016/j.cgh.2015.10.022 108 WatanabeT.NishioH.TanigawaT.YamagamiH.OkazakiH.WatanabeK.et al (2009)
The present review highlights the role of GSH and related cytoprotective effects in the susceptibility to carcinogenesis and in the sensitivity of tumors to the cytotoxic effects of anticancer agents
The CD14(+/low)CD16(+) monocyte subset is more susceptible to spontaneous and oxidant-induced apoptosis than the CD14(+)CD16(-) subset
Peripheral nerves are capable of regeneration and, when injury occurs, may cause neuropathic pain in the peripheral nervous system (PNS)
