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Mol Microbiol 43:13471358

However, when the balance is thrown off and there is an excess of oxidative stress, it can be quite destructive

Despite these promising findings, some preclinical models have also reported paradoxical pro-tumor effects or significant adverse outcomes, such as exacerbating metastasis and cachexia, under specific conditions, highlighting context-dependent responses [148, 149]
Tankyrase, a poly(ADP-ribose) polymerase at human telomeres
