glutathione s transferase antioxidant Overexpression of S-Transferases in Human Diseases: Drug Targets and Therapeutic Implications Effect of antioxidant supplement on

In relation to COX-2, polyphenols may have several effects: (i) Some studies have suggested that polyphenols may inhibit COX-2 activity [239], and (ii) wine polyphenols have been shown to exert an antineoplastic effect on the androgen-resistant PC-3 cell line through inhibition of NF--mediated transcriptional activity of the COX-2 promoter

We're dealing with more complex conditions

Pinpointing novel risk loci for Lewy body dementia and the shared genetic etiology with Alzheimers disease and Parkinsons disease: a large-scale multi-trait association analysis

Typical observations include persistent fever, elevated inflammatory markers (eg, D-dimer, ferritin) and elevated pro-inflammatory cytokines, which have all been associated with critical and fatal diseases