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However, the pooled analysis did not show significantly lower disability progression: 12-week worsening of disability was 5.2% in the ublituximab group compared to 5.9% in the teriflunomide group

Across all six studies, the safety findings were consistent: no serious adverse events, no immunogenic responses, no changes in IGF-1, no glucose or insulin disruption
Whether GHK-Cu produces lasting skin changes, whether tolerance develops, and whether long-term copper exposure in skin has adverse effects are unanswered questions

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