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Compared with control groups, omega-3 supplementation had no significant effect on urine protein excretion or glomerular filtration rate

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To induce DSBs, cells were treated with Z-(4)-Hydroxytamoxifen (Millipore Sigma, Cat#H7904, 1M) and Shield-1 (TaKaRa, Cat#632189, 1M) for a period of 4 hours in charcoal stripped FBS containing medium

One key mechanism involved ER stress, evidenced by increased expression of proteins like C/EBP homologous protein and activation of caspases 12 and 3