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Very small individuals (under 50kg) might start at the lower end of dose ranges

B12 plays a role in producing mood-regulating neurotransmitters, helping to alleviate symptoms of stress, anxiety, and depression

3.3 Changes in serum cobalamin by supplementation route and dosage Across 35 comparisons, the mean percentage increase in serum cobalamin following supplementation was approximately 293%, confirming the overall effectiveness of vitamin B12 interventions (Supplementary Table S4)

Benefits of Combining B12 with Semaglutide Combating Fatigue : Vitamin B12 can help reduce feelings of tiredness and weakness, supporting energy levels during semaglutide therapy