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Description
The involvement of the Notch-1 is associated with the advancement and spread of this neoplasia in GC [156]
In particular, menadione (2-methyl-1,4-naphthoquinone) or vitamin K3 is essential in the body for the synthesis of blood coagulation factors [141]
Extrinsic apoptosis dominates as ROS synergize with death receptor signaling (e.g., TNFR/Fas), activating caspase-8 through DISC formation
The aim is to rapidly raise NAD+ levels so it can enter cells quickly
