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B12 deficiency becomes increasingly common with age due to atrophic gastritis, reduced intrinsic factor production, and polypharmacy

Growing evidence supports that MSCs exert their anti-oxidant effects through a range of mechanisms, including direct scavenging of free radicals, upregulating host anti-oxidant defenses, immunomodulation via ROS suppression, enhancing cellular respiration and mitochondrial functions, and donating functional mitochondria to damaged hepatocytes [106]

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Recent studies have found that supplementing glycyrrhizin in colitis mice upregulates ferritin expression, increases cellular iron storage, lowers cellular iron levels, and further inhibits ferroptosis in the colitis model epithelial cells [275]