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A reduction of spontaneous action potential-dependent inhibitory transmission has been described in other neurological disorders where E/I balance is altered (for instance, in epilepsy due to irradiation induced cortical dysplasia and heterotopy [69])

A repeated-measures 1-way ANOVA test was used to assess differences of baseline plasma concentrations of BB and TMAO between multiple visits

Iwanaga, J., Wilson, C., Lachkar, S., Tomaszewski, K

72 Nevertheless, it does not assess known cardiometabolic risk factors such as stress, social isolation, and physical inactivity, and does not incorporate information about family history, mental health and sleep disorders, and other non-metabolic/non-renal chronic inflammatory conditions