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Hypoxic epithelial necrosis triggers neutrophilic inflammation via IL-1 receptor signaling in cystic fibrosis lung disease

Nonnas are driven by purpose rather than ambition, unlike typical biohacking enthusiasts who, to use Greenfields terms, are often sad unfulfilled billionaires or super athletes

Neurology 88 , 19581967 (2017)

In a systematic review and meta-analysis, depression was associated with significantly increased oxidative stress as measured by biomarkers of oxidative DNA damage (8-OHdG) and lipid peroxidation (F-isoprostanes) compared to non-depressed controls ( 3.5 Neurotrophic deficits and impaired hippocampal neurogenesis The diminishment of neurotrophic signaling, especially that related to brain-derived neurotrophic factor (BDNF), stands as a defining characteristic of depression