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Withdrawing tirzepatide in the SURMOUNT-4 trial resulted in a significant weight gain (14%), while continuing treatment preserved and increased the initial weight loss (5.5%) [74]

Methotrexate (MTX) is a folate antagonist medication widely used as both a chemotherapy agent and a disease-modifying antirheumatic drug (DMARD) for autoimmune diseases such as rheumatoid arthritis and psoriasis

Some signs that you may have a B12 deficiency include symptoms like fatigue, cognitive issues like brain fog, low energy, feelings of weakness, and tingling or numbness in the limbs