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Description
Of the eight GPxs, GPx4 is essential for life as the mice lacking it (knock out or KO) do not survive [1, 8, 9]

Selenium mitigates ferroptosis-mediated dopaminergic cell death by regulating the Nrf2/GPX4 pathway

Knuckles P, Lence T, Haussmann IU, Jacob D, Kreim N, Carl SH, et al

Inhibition of human erythrocyte glutathione S-transferase by some flavonoid derivatives
