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BlasbalgT.HibbelnJ.RamsdenC.et al.2011Changes in consumption of omega-3 and omega-6 fatty acids in the United States during the 20th century

Furthermore, Bui et al (71) demonstrated that treatment of intestinal epithelial cells or hepatocytes with SCFAs, particularly butyrate, notably upregulated the expression and activity of 17-hydroxysteroid dehydrogenase and 3-hydroxysteroid dehydrogenase

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The present findings are therefore consistent with prior evidence suggesting dysregulated amino acid metabolism in at least a subset of individuals with ASD, while also underscoring the metabolic diversity observed across the spectrum [16, 17, 30, 31]