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Furthermore, accumulation of L-DOPA in the cell supernatant can cause toxicity and impair growth 31 a trend observed in gsh2 mutants grown in L-DOPA medium, which was rescued with 50 M GSH supplementation (Extended Data Fig

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In contrast, the study of GSH-Pxs in prokaryotes remains underexplored, and they have been reported only in Streptococcus pyogenes , where a gsh-px mutant was associated to an impaired virulence in mice infection models [13]